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Philip O Livingston Selected Research

keyhole-limpet hemocyanin (keyhole limpet hemocyanin)

1/2012Immunization with N-propionyl polysialic acid-KLH conjugate in patients with small cell lung cancer is safe and induces IgM antibodies reactive with SCLC cells and bactericidal against group B meningococci.
9/2009Synthesis of sialyl Lewis(a) (sLe (a), CA19-9) and construction of an immunogenic sLe(a) vaccine.
7/2007Pilot study of a heptavalent vaccine-keyhole limpet hemocyanin conjugate plus QS21 in patients with epithelial ovarian, fallopian tube, or peritoneal cancer.
9/2005Identification of DHBcAg as a potent carrier protein comparable to KLH for augmenting MUC1 antigenicity.
5/2005Comparison of antigen constructs and carrier molecules for augmenting the immunogenicity of the monosaccharide epithelial cancer antigen Tn.
9/2004Vaccination of patients with small-cell lung cancer with synthetic fucosyl GM-1 conjugated to keyhole limpet hemocyanin.
7/2004A fully synthetic therapeutic vaccine candidate targeting carcinoma-associated Tn carbohydrate antigen induces tumor-specific antibodies in nonhuman primates.
2/2004Vaccination of small cell lung cancer patients with polysialic acid or N-propionylated polysialic acid conjugated to keyhole limpet hemocyanin.
12/2003Fully synthetic carbohydrate-based vaccines in biochemically relapsed prostate cancer: clinical trial results with alpha-N-acetylgalactosamine-O-serine/threonine conjugate vaccine.
11/2003Consistent antibody response against ganglioside GD2 induced in patients with melanoma by a GD2 lactone-keyhole limpet hemocyanin conjugate vaccine plus immunological adjuvant QS-21.
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Philip O Livingston Research Topics

Disease

29Neoplasms (Cancer)
11/2013 - 01/2002
15Melanoma (Melanoma, Malignant)
06/2010 - 05/2002
5Breast Neoplasms (Breast Cancer)
10/2010 - 02/2002
4Brain Neoplasms (Brain Tumor)
06/2006 - 06/2002
3Adenocarcinoma
11/2013 - 05/2002
3Communicable Diseases (Infectious Diseases)
08/2012 - 02/2010
3Small Cell Lung Carcinoma (Small Cell Lung Cancer)
01/2012 - 02/2004
2Disease Progression
01/2012 - 10/2010
2Neoplasm Metastasis (Metastasis)
03/2011 - 09/2009
2Neoplasm Micrometastasis
05/2006 - 11/2003
2Prostatic Neoplasms (Prostate Cancer)
07/2004 - 12/2003
1Cognitive Dysfunction
08/2012
1Peripheral Nervous System Diseases (PNS Diseases)
01/2012
1Ataxia (Dyssynergia)
01/2012
1Weight Loss (Weight Reduction)
05/2011
1Lymphoma (Lymphomas)
05/2011
1Lung Neoplasms (Lung Cancer)
03/2011
1Ovarian Neoplasms (Ovarian Cancer)
03/2009
1Circulating Neoplastic Cells
05/2006
1Carcinoma (Carcinomatosis)
07/2004
1Lymphopenia (Lymphocytopenia)
02/2004

Drug/Important Bio-Agent (IBA)

23VaccinesIBA
09/2013 - 01/2002
17AntibodiesIBA
09/2013 - 01/2002
16AntigensIBA
09/2013 - 01/2002
14saponin QA-21V1 (QS21)IBA
08/2012 - 02/2002
11keyhole-limpet hemocyanin (keyhole limpet hemocyanin)IBA
01/2012 - 10/2003
9SaponinsIBA
08/2012 - 10/2003
9CarbohydratesIBA
05/2011 - 05/2002
8Immunologic Adjuvants (Immunologic Adjuvant)IBA
01/2012 - 05/2002
7Complement System Proteins (Complement)IBA
09/2013 - 01/2002
6Monoclonal AntibodiesIBA
11/2013 - 05/2002
5Immunoglobulin M (IgM)IBA
09/2013 - 09/2004
5Peptides (Polypeptides)IBA
05/2011 - 02/2002
5Conjugate VaccinesIBA
02/2010 - 01/2002
5Temozolomide (Temodar)FDA LinkGeneric
06/2006 - 06/2002
4Globo-HIBA
05/2011 - 10/2003
4Thalidomide (Thalomid)FDA Link
06/2005 - 06/2002
3Surface Antigens (Surface Antigen)IBA
09/2013 - 10/2003
3GlycolipidsIBA
09/2009 - 01/2002
3Monophenol Monooxygenase (Tyrosinase)IBA
12/2008 - 05/2002
3Combined VaccinesIBA
07/2007 - 01/2002
3MucinsIBA
05/2005 - 01/2002
2Neural Cell Adhesion Molecules (Neural Cell Adhesion Molecule)IBA
01/2012 - 02/2004
2polysialic acidIBA
01/2012 - 02/2004
2GD2 gangliosideIBA
05/2011 - 11/2003
2CA-19-9 Antigen (CA 19-9 Antigen)IBA
03/2011 - 09/2009
2Glycoproteins (Glycoprotein)IBA
10/2010 - 09/2009
2GlycopeptidesIBA
10/2010 - 07/2004
2Proteins (Proteins, Gene)FDA Link
10/2010 - 05/2005
2Biological ProductsIBA
02/2010 - 04/2003
2DNA (Deoxyribonucleic Acid)IBA
12/2008 - 11/2007
2Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA
12/2008 - 05/2002
2Differentiation AntigensIBA
11/2007 - 05/2006
2Immunoglobulin G (IgG)IBA
09/2005 - 07/2004
2Serine (L-Serine)FDA Link
05/2005 - 12/2003
2Threonine (L-Threonine)FDA Link
05/2005 - 12/2003
2GD3 ganglioside (GD(3))IBA
07/2004 - 01/2002
1Biomarkers (Surrogate Marker)IBA
11/2013
1WortmanninIBA
09/2013
1GangliosidesIBA
09/2013
1dactolisibIBA
09/2013
1PolymersIBA
01/2012
1astragaloside IIIBA
05/2011
1astragaloside AIBA
05/2011
1FlavonoidsIBA
05/2011
1Huang QiIBA
03/2011
1AutoantibodiesIBA
10/2010
1AmidesIBA
02/2010
1GPI0100IBA
09/2009
1SelectinsIBA
09/2009
1LigandsIBA
09/2009
1Carrier Proteins (Binding Protein)IBA
07/2009
1maleimideIBA
07/2009
1OligosaccharidesIBA
03/2009
1Cancer VaccinesIBA
12/2008
1Xylose (D-Xylose)FDA Link
01/2008
1DNA VaccinesIBA
11/2007
1AutoantigensIBA
11/2007
1HLA Antigens (Human Leukocyte Antigens)IBA
11/2007
1HLA-A*02:01 antigenIBA
11/2007
1vitespinIBA
08/2007
1NitrogenIBA
08/2007
1Heat-Shock Proteins (Heat-Shock Protein)IBA
08/2007
1sialyl-Tn antigen-keyhole-limpet hemocyanin conjugateIBA
05/2007
1Epithelial Cell Adhesion MoleculeIBA
05/2005
1Amino AcidsFDA Link
05/2005
1Polystyrenes (Polystyrene)IBA
05/2005
1DisaccharidesIBA
05/2005
1A-factor (Streptomyces)IBA
05/2005
1MonosaccharidesIBA
05/2005
1fucosyl GM1 gangliosideIBA
09/2004
1Tn antigenIBA
07/2004
1GlycoconjugatesIBA
07/2004
1GD3-lactone-KLHIBA
07/2004

Therapy/Procedure

5Therapeutics
03/2011 - 05/2002
2Aftercare (After-Treatment)
09/2005 - 11/2003
2Immunotherapy
09/2004 - 07/2004
1Surgical Amputation (Amputations)
05/2011
1Injections
11/2007
1Drug Therapy (Chemotherapy)
06/2005